Preheat your oven to 450°F. Line a baking sheet with foil and coat with nonstick cooking spray.
In a large resealable bag, combine panko breadcrumbs, garlic powder, onion powder, smoked paprika, sea salt, and black pepper. Seal and shake to mix.
Crack the egg into a shallow dish and beat lightly. Dip each chicken tender into the egg, then place into the bag with the panko mixture. Seal and shake to coat the chicken evenly.
Place the coated chicken tenders on the prepared baking sheet in a single layer. Spray the top of each tender lightly with cooking spray.
Bake in the preheated oven for 7 minutes. Flip each tender and continue to bake for another 7 minutes, or until the chicken is cooked through.
For an extra crunch, move the oven rack closer to the broiler and broil the tenders for 1-2 minutes. Watch them closely as they can burn easily.
Remove from the oven and let rest for a couple of minutes before serving.
